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http://lib.osau.edu.ua/jspui/handle/123456789/4838| Title: | NEW MODEL OF PHARMACORESISTANCE EPILEPSY |
| Authors: | Boiko Yu. A., Boiko I. A. |
| Keywords: | new model, pharmacoresistance, epilepsy |
| Issue Date: | 2022 |
| Publisher: | Поліський національний університет |
| Citation: | Boiko Yu. A., Boiko I. A. New model of pharmacoresistance epilepsy. Сучасний стан розвитку ветеринарної медицини, науки і освіти : мат-ли Міжнар. наук.-практ. конф., присв. 35-річчю засн. ф-ту вет. медицини (м. Житомир, 12-13 жовтня 2022 р.) / Поліський національний університет. Житомир. 2022. С. 147-148. |
| Abstract: | Interest in epilepsy is caused by both the widespread occurrence of this pathology and the severity of its course. The most common treatment option is pharmacotherapy with antiepileptic drugs (AEDS). The efficiency of using AEDs depends on the activity of metabolic and biotransformation processes. The cytochrome P450 system is an important enzymatic system participating in the biotransformation of medicinal substances, including antiepileptic drugs. The activity of the cytochrome P450 system depends on the characteristics of the combinations of individual enzyme isoforms that represent it and are determined by the human genotype. |
| URI: | http://lib.osau.edu.ua/jspui/handle/123456789/4838 |
| Appears in Collections: | Бойко Юрій Олександрович |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Boiko Yu. A., Boiko I. A..pdf | 281,51 kB | Adobe PDF | View/Open |
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