КЛІНІКО-МОРФОЛОГІЧНІ ОСОБЛИВОСТІ ПЕРЕБІГУ ВНУТРІШНЬОГО ЕНДОМЕТРІОЗУ У ПОЄДНАННІ З ЕНДОМЕТРІОЇДНОЮ КАРЦИНОМОЮ ЕНДОМЕТРІЮ У ЖІНОК В ПОСТМЕНОПАУЗІ

Abstract

The article is devoted to the research of the clinical and morphological features of adenomyosis (AD) in the presence of the endometrioid carcinoma (EC) of uterine in postmenopausal patients. The analysis was made of clinical and morphological manifestations of this disease in 11 women aged 58–74 years. Morphological structure of eu- and ectopic endometrium was studied at work in detail, according to comorbidity. It was diagnosed that for the morphological picture of AD in the presence of EC characteristic the predominance of the diffuse form of AD above the nodal, presence of active AD and inactive AD. It was confirmed the possibility of the combination of AD and EC with endometrial hyperplasia and mioma of the uterine body. There was marked increase in the expression levels of ER-receptor in accordance with the degree of EC differentiation. It established that the fire of AD in the presence of the EC retain their estrogen activity.