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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1921

Авторы: Гуніч В. В. та ін.
Гунич В.В. и др.
Gunich V. and etc.
Ключевые слова: коти, хронічна ниркова недостатність, серце, макроскопічні зміни, мікроскопічні зміни
cats, chronic kidney insufficiency, heart, macroscopic changes, microscopic changes
Issue Date: 2015
Издатель: Ін-т експерим. і клініч. вет. медицини
Библиографическое описание: УДК 619:616.61-008.6:636.8 Гуніч В. В. Патоморфологічні зміни в серці котів при хронічній нирковій недостатності / В.В. Гуніч та ін. // Ветеринарна медицина: міжвід. темат.наук.зб. - Харків, 2015. - Вип.100. - С. 147-149.
Аннотация: Приведено результати патоморфологічних досліджень серця котів, які загинули внаслідок хронічної ниркової недостатності. Встановлено, що макроскопічно в серці котів, які загинули від цієї патології, виявляються ознаки, характерні для серцевої недостатності. Мікроскопічно в міокарді встановлюють набряк інтерстицію, зернисту дистрофію, руйнування та некроз кардіоміоцитів. Артерії та вени в стромі органу частково спазмовані, у них виявляється сладж-феномен.
Purpose of researches - in detail to learn pathomorphological changes in the heart of cats at chronic kidney insufficiency. Material and methods of researches. At life diagnosis on chronic kidney insufficiency for all cats was set complex taking into account anamnesis, clinical signs, results of laboratory analyses of blood and urine. A pathoanatomical dissection was conducted by the method of the partial evisceretion. Paraffin cuts from the pieces of kidneys of cats painted by the hematoxylin and eosin. Results of researches. It is set on a dissection, that heart small the dulled apex, him right and left ventricle were extended. Myocardium had a grayish color placed. During realization of histological researches in an epicardium and endocardium microscopic changes were absent. However between these shells of heart and myocardium the edema of different intensity appeared on many areas. In myocardium artery and part of veins were partly spasmed. The sladg-phenomenon was registered in inlightening of blood vessels of different types. Stroma of myocardium was strongly swollen. A less expressive edema appeared between the separated fibers of cardiomiocytes. All cardiomiocytes were in a state of grain dystrophy. In parts of the dystrophically changed cells disintegration of their cytoplasm was registered on the separate, clearly separated one from other fragments of the rounded and oval form. Satellite cells moved away from part of dystrophically changed cardiomiocytes. In a cytoplasm of some cells of myocardium the not painted by eosin vacuoles was appeared. Part of dystrophic changed cardiomiocytes was collapsed. Destruction of part of cardiomiocytes resulted in fragmentation of part of their fibers. On the separate, small sizes areas of myocardium total necrosis and destruction of cardiomiocytes was registered. Conclusions. 1. Grossly in the heart of cats which died from chronic kidney insufficiency, signs, characteristic for a heart failure, appear. 2. Microscopically in myocardium set an edema to the interstitium, grain dystrophy, destruction and necrosis of cardiomiocytes. 3. Arteries and veins in the stroma of organ are partly spasmed, the sladg-phenomenon appears in them.
URI: http://hdl.handle.net/123456789/1921
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